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It fits four parameters: the bottom and top plateaus of the curve, the EC50 (or IC50), and the slope factor (Hill slope). This curve is symmetrical around ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

EC50 is the concentration of agonist that gives a response half way between ... Depending on which units Y is expressed in, and the values of Bottom and Top, the ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

response curves follow the familiar symmetrical sigmoidal shape. The goal is to determine the EC50 of the agonist - the concentration that provokes a response ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Equation: EC50 shift; Equation: Allosteric EC50 shift; Equation: ECanything; Equation: Absolute IC50. Dose-response -- Special (X is Log[Concentration]) ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Equation: EC50 shift; Equation: Allosteric EC50 shift; Equation: ECanything; Equation: Absolute IC50. Receptor binding - Key concepts; Receptor binding ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

The only difference is that the inhibitory equations fit the IC50 ("I" for inhibition) while the stimulation equations fit the EC50 ("E" for effective).

https://www.graphpad.com/guides/prism/latest/curve-fitting/

EC50 (effective concentration) is the concentration of drug that elicits a response halfway between the baseline and maximum response (dose-response curves ...

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The EC50, fit by standard dose-response models, is determined by two properties of the agonist: •How well it binds to the receptor, quantified by the ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

The EC50 is determined by two properties of the agonist: •How well it binds to the receptor, quantified by the affinity of the drug for binding to its ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

... EC50, but you want to also report the EC50. Enter the label 'EC50' on the left and '10^logEC50' on the right (without the quotes). Example: You fit data to ...

https://www.graphpad.com/guides/prism/7/curve-fitting/