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This model fits entire dose-response curves determined in the absence and presence of a modulator. The goal is to learn the affinity of the modulator for ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

You should average the logEC50 values, not the EC50 values. Since the distribution of EC50s is usually not symmetrical, the mean of the EC50s is not a good way ...

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The EC50 is defined quite simply as the concentration of agonist that provokes a response halfway between the baseline (Bottom) and maximum response (Top). It ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

IC50 and EC50 are, respectively, the inhibition and effective concentrations that produce 50% of maximal response from a drug or treatment dose.

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The 95% confidence interval of the EC50 is not symmetrical. Sample data. Asymmetrical confidence intervals. The sample data above were fit to the model: ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

The EC50 is the dose of a drug that provokes a response half-way between the top plateau and bottom plateau of the dose response curve. Unless you constrain the ...

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EC50 and LogEC50: EC50 is the concentration of agonist that gives half maximal response in the absence of inhibitor. The logEC50 is in the same units you used ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

The dose-response model has four parameters: the bottom plateau, the top plateau, the EC50, and the slope factor (which is often constrained to a standard ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

Prism 7 can report asymmetrical confidence intervals for parameters fit by nonlinear regression. You can ask it to compute this kind of CI for the IC50 or EC50 ...

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Choose an equation where X is expected to be dose or concentration, and Prism will fit the EC50 or IC50 directly, with standard errors.

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