KNOWLEDGEBASE - ARTICLE #389

What published papers document the superiority of nonlinear regression over Scatchard analyses and similar linearizing techniques?

Bürgisser, E. (1984) Radioligand-receptor binding studies: what's wrong with the Scatchard analysis? Trends Pharmacol. Sci. 5:142-144.

Hall, H. (1992) Saturation analysis in receptor binding assays: An evaluation of six different calculation techniques. Pharmacol. Toxicol. 71:45-51.

Munson, P. J. (1983) LIGAND: A computerized analysis of ligand binding data. Methods Enzymol. 92:543-576.

Munson, P. J., and Rodbard, D. (1980) LIGAND: A versatile computerized approach for characterization of ligand-binding systems. Anal. Biochem. 107:22-239.

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