KNOWLEDGEBASE - ARTICLE #1253

Can Prism compute the mean (rather than median) survival time?

Survival analysis computes the median survival with its confidence interval, not the mean.

The reason for this is that the median survival time is completely defined once the survival curve descends to 50%, even if many other subjects are still alive. And the median survival is defined, even if data from some subjects were censored. 

In contrast, the mean survival is simply not defined until every subject dies, and only when you know the survival time for each subject (none were censored). These conditions occur in very very few studies, so Prism doesn't compute mean survival. Mean survivals are reported rarely in survival experiments.

But there is an easy workaround if you knowthee survival times for each subject. Enter them into a column table, and ask Prism to do column statistics (descriptive statistics with Prism 8 and later) to calculate the mean with its confidence interval.



Keywords: mean survival, average survival, median survival

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