Bug. Graphs using text as symbols created with Prism 5.00-5.02 or 5.0a-5.0b look different when opened with newer versions.
Prism 5 lets you plot data using any character from any font instead of a built-in symbol (i.e. circles, squares..). To do this, from the Format Graph dialog, drop the Shape menu showing the built-in symbols, click "More...", and choose the character and font.
If you did this using early releases of Prism 5 (5.00-5.02, or 5.0a-5.0b), there is a problem. When you open the file using any newer release of Prism, the symbol will revert to a built-in symbol. The only way to fix this is to go back to the Format Graph dialog, and choose the character and font again.