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Half-way between is 500.5, so the EC50 is the X value (concentration) that provokes a response of 500.5. Now transform the Y values to logarithms (base 10). The ...

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You can either compute these values from the EC 50 or fit a curve in such a way as to directly fit EC anything.

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This calculator computes EC 80 or EC 90 (etc.) from EC 50. How? 1. Enter EC 50 I will enter: EC 50 as concentration. For 1nM, enter '1e-9'.

https://www.graphpad.com/quickcalcs/ecanything1/

The EC50 is the concentration that gives a response half way between the bottom and top plateaus of the curve. If the bottom cannot be defined accurately, ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

It fits a family of curves, to determine the EC 50 of the control curve as well as two parameters (K b and alpha) that describe the allosteric interaction of a ...

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This is the difference between the two logEC50s, which is equivalent to the log of the ratio of the two EC50s. Take the antilog of these values to convert to a ...

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Many dose-response curves follow a familiar sigmoidal shape. These curves are often defined by four parameters: Top, Bottom, Hill slope, and the EC50 (or IC50).

https://www.graphpad.com/guides/prism/latest/curve-fitting/

The pEC50 is defined as the negative logarithm of the EC50. If the EC50 equals 1 micromolar (10 -6 molar), the log(EC50) is -6 and the pEC50 is 6.

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Model ... EC50Control is the concentration of agonist that gives half maximal response in the absence of modulator. Top and Bottom are plateaus in the units of ...

https://www.graphpad.com/guides/prism/latest/curve-fitting/

"EC" means effective concentration, and is used for dose-response curves that go up hill. Sometimes it is also used for a curve that goes downhill.

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