Prism's nonlinear regression dialog has ten tabs (eleven if you're running nonlinear regression from the multiple variables data table), explained in this portion of the guide. It can seem overwhelming at first. But you don't have to learn about all the choices when you first fit a curve. Start by focusing on the selecting an appropriate model in the Model tab, and then learn about the other choices later.
•Before learning all the details, first understand the big picture -- the basic steps required to fit a model to data.
•So many choices! Which ones are essential?