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InStat is available for both Windows and Mac!
Macworld gives "4 mice" rating to InStat 3 for Mac!
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InStat 3 upgrading information

Already own InStat?  You can upgrade your current copy to InStat 3.  Here’s everything you need to know.

Upgrade Costs
You may upgrade any version of InStat to InStat 3 for $79.00
One upgrade per serial number. All prices are in US dollars.

Upgrading Networks
If you own a network license and you want to upgrade your software, you need to upgrade the entire network license at the same time. 

Licensing Agreement
Your upgrade will mean that you have transferred your license from your old version of the program to InStat 3.  Please note that after purchasing an upgrade, you don’t own more licenses than you did before. Your old serial number is no longer valid and, because your old license no longer exists, it’s a violation of your license agreement if you let someone else use your prior version while you use InStat 3.

How to Order
To order your upgrade, you'll need to tell us the serial number of your current version. To find your serial number, run InStat then drop the Help (Windows), Apple (Mac OS 8–9) and choose "About GraphPad InStat". If you have any problems, email sales@graphpad.com.