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An in-depth guide to dose response curves
While overkill for most pharmacologists, this is a unique resource for people who need to deal with complex dose-response relationships, including allosteric interactions, synergy, multi-step binding, cubic binding models and much more. It deals only with systems at equilibrium, so does not cover kinetics. If you are curious, start with this chapter, which explains many variations on the Hill equation, and the many uses of the term "logistic". If you haven't heard of the Hill equation, this book is not for you!
Drug-Acceptor Interactions: Modeling theoretical tools to test and evaluate experimental equilibrium effects. by Neils Bindslev, Coaction Publishing ISBN: 978-91-977071-0-7. Freely available online or order the book.
|Book Title:||Drug-Acceptor Interactions - Modeling theoretical tools to test and evaluate experimental equilibrium effects|
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