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Table of contents
Intro to regression
Nonlinear regression


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Introduction
Choices
You must pick model
Classic models
How to derive
Sum-of-squares
Weighting
How nonlin works
Curve fitting with Prism
Interpreting the results
Comparing two curves
Distributions of best-fit values
Radioligand binding
Saturation binding
Competitive binding
Kinetics of binding
Dose-response curves
Enzyme kinetics
Standard curves
More information
Search curvefit.com

curvefit.com was created by GraphPad Software, Inc. Send comments or questions to the author of these pages, Dr. Harvey Motulsky, president of GraphPad Software.

In April 2003, GraphPad released Prism 4 and published Fitting Models to Biological Data using Linear and Nonlinear Regression. This book includes all the information that comprises curvefit.com, and much more. You can read this book as a pdf file.



Classic equations commonly used by biologists

In most fields of biology, and many other fields of science, the models (equations) listed below are used very frequently. All are all built in to GraphPad Prism.

One site binding (hyperbola)
Two site binding
Sigmoidal dose-response
Sigmoidal dose-response (variable slope)
One site competition
Two site competition
Boltzmann sigmoid
One phase exponential decay
Two phase exponential decay
One phase exponential association
Two-phase exponential association
Exponential growth
Power series
Polynomial equations
Sine wave
Gaussian distribution                                                                                                                                                                                                                                                                                                           
How models are derived

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